Role of diastolic vortices in flow and energy dynamics during systolic ejection

MRI-based computational fluid dynamics simulations were performed in the left ventricles of two adult porcine subjects with varying physiological states (before and after an induced infarction). The hypothesis that diastolic vortices store kinetic energy and assist systolic ejection was tested, by p...

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Bibliographic Details
Published in:Journal of biomechanics 2019-06, Vol.90, p.50-57
Main Authors: Vasudevan, Vivek, Low, Adriel Jia Jun, Annamalai, Sarayu Parimal, Sampath, Smita, Chin, Chih-Liang, Ali, Asad Abu Bakar, Yap, Choon Hwai
Format: Article
Language:English
Subjects:
Apical washout
Computational fluid dynamics
Computer applications
Computer simulation
Diastole
Diastolic vortices
Energy
Energy dissipation
Fluid dynamics
Fluid flow
Heart rate
Heart valves
Infarction
Intra-cardiac fluid mechanics
Kinetic energy
Left ventricle
Magnetic resonance imaging
Mitral valve
Physiology
Systole
Velocity distribution
Vortex rings
Vortices
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Summary:MRI-based computational fluid dynamics simulations were performed in the left ventricles of two adult porcine subjects with varying physiological states (before and after an induced infarction). The hypothesis that diastolic vortices store kinetic energy and assist systolic ejection was tested, by performing systolic simulations in the presence and absence of diastolic vortices. The latter was achieved by reinitializing the entire velocity field to be zero at the beginning of systole. A rudimentary prescribed motion model of a mitral valve was included in the simulations to direct the incoming mitral jet towards the apex. Results showed that the presence or absence of diastolic vortex rings had insignificant impact on the energy expended by walls of the left ventricles for systolic ejection for both the porcine subjects, under all physiological conditions. Although substantial kinetic energy was stored in diastolic vortices by end diastole, it provided no appreciable savings during systolic ejection, and most likely continued to complete dissipation during systole. The role of diastolic vortices in apical washout was investigated by studying the cumulative mass fraction of passive dye that was ejected during systole in the presence and absence of vortices. Results indicated that the diastolic vortices play a crucial role in ensuring efficient washout of apical blood during systolic ejection.
ISSN:0021-9290
1873-2380
DOI:10.1016/j.jbiomech.2019.04.026