Predictors of Acute Kidney Injury Following Aortic Arch Surgery

Acute kidney injury (AKI) following open aortic arch surgery is a frequent complication associated with increased morbidity and mortality. The primary purpose of this study was to evaluate risk factors for postoperative AKI in patients who underwent open aortic arch surgery utilizing hypothermic cir...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of surgical research 2019-10, Vol.242, p.40-46
Main Authors: Ghincea, Christian V., Reece, T. Brett, Eldeiry, Mohamed, Roda, Gavriel F., Bronsert, Michael R., Jarrett, Michael J., Pal, Jay D., Cleveland, Joseph C., Fullerton, David A., Aftab, Muhammad
Format: Article
Language:English
Subjects:
Acute kidney injury
Acute Kidney Injury - diagnosis
Acute Kidney Injury - epidemiology
Acute Kidney Injury - etiology
Adult
Aged
Aorta, Thoracic - surgery
Aortic arch surgery
Blood Transfusion - statistics & numerical data
Cardiopulmonary bypass
Cardiopulmonary Bypass - adverse effects
Cardiopulmonary Bypass - statistics & numerical data
Circulatory Arrest, Deep Hypothermia Induced - adverse effects
Female
Hemiarch surgery
Hospital Mortality
Humans
Hypothermic circulatory arrest
Incidence
Male
Middle Aged
Postoperative Complications - diagnosis
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Predictors
Prognosis
Retrospective Studies
Risk Assessment - statistics & numerical data
Risk Factors
Time Factors
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Acute kidney injury (AKI) following open aortic arch surgery is a frequent complication associated with increased morbidity and mortality. The primary purpose of this study was to evaluate risk factors for postoperative AKI in patients who underwent open aortic arch surgery utilizing hypothermic circulatory arrest (HCA). Included were 295 patients undergoing surgery between January 2011 and March 2018. AKI was defined according to Kidney Disease: Improving Global Outcomes guidelines. Preoperative and intraoperative variables were stratified by no AKI versus any AKI, and bivariate analysis was performed. Multivariable logistic regression analysis used statistically and clinically significant characteristics from the bivariate analysis. Of the 295 patients, 93 (32%) developed AKI. In the bivariate analysis, significant predictors of AKI included the following: history of hypertension (P 
ISSN:0022-4804
1095-8673
DOI:10.1016/j.jss.2019.03.055