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Comparison of Samfilcon A and Lotrafilcon B silicone hydrogel bandage contact lenses in reducing postoperative pain and accelerating re-epithelialization after photorefractive keratectomy

Purpose To compare the efficacy of Samfilcon A and Lotrafilcon B bandage contact lenses after photorefractive keratectomy (PRK). Methods In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surge...

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Published in:International ophthalmology 2019-11, Vol.39 (11), p.2569-2574
Main Authors: Yuksel, Erdem, Ozulken, Kemal, Uzel, Mehmet Murat, Taslipinar Uzel, Ayse Guzin, Aydoğan, Semih
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container_title International ophthalmology
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creator Yuksel, Erdem
Ozulken, Kemal
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description Purpose To compare the efficacy of Samfilcon A and Lotrafilcon B bandage contact lenses after photorefractive keratectomy (PRK). Methods In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surgery and on postoperative days 1, 2 and 3. Slit biomicroscopy was performed to assess epithelial defect size in the postoperative examinations. The subjective evaluation of pain and visual symptoms was recorded on postoperative days 1, 2 and 3. Results Analysis was made of 68 eyes of 34 patients who fulfilled the criteria and had PRK for correction of low to moderate myopia/astigmatism. On postoperative days 1 and 2, pain and epiphora scores were significantly lower in eyes with Samfilcon A lens ( p  
doi_str_mv 10.1007/s10792-019-01105-9
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Methods In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surgery and on postoperative days 1, 2 and 3. Slit biomicroscopy was performed to assess epithelial defect size in the postoperative examinations. The subjective evaluation of pain and visual symptoms was recorded on postoperative days 1, 2 and 3. Results Analysis was made of 68 eyes of 34 patients who fulfilled the criteria and had PRK for correction of low to moderate myopia/astigmatism. On postoperative days 1 and 2, pain and epiphora scores were significantly lower in eyes with Samfilcon A lens ( p  &lt; 0.001 for all), and on postoperative day 3, the differences were not significant ( p  = 0.414 and p  = 0.180, respectively). There was no significant difference between the two lenses in respect of the levels of photophobia. The difference in epithelial defect size was statistically lower in eyes with Samfilcon A lens compared to Lotrafilcon B on day 1 (16.89 mm 2 vs. 21.07 mm 2 ; p  = 0.003) and day 2 (1.49 mm 2 vs. 2.46 mm 2 ; p  &lt; 0.001). The difference was not significant on day 3. (0.05 mm 2 vs. 0.05 mm 2 ; p  = 1.000). Conclusions The Samfilcon A lens is superior to the Lotrafilcon B lens in reducing postoperative pain and accelerating re-epithelialization.</description><identifier>ISSN: 0165-5701</identifier><identifier>EISSN: 1573-2630</identifier><identifier>DOI: 10.1007/s10792-019-01105-9</identifier><identifier>PMID: 31065904</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Adolescent ; Adult ; Astigmatism ; Bandages, Hydrocolloid ; Contact lenses ; Contact Lenses, Hydrophilic ; Equipment Design ; Eye ; Eye (anatomy) ; Female ; Follow-Up Studies ; Humans ; Hydrogels ; Hydrogels - pharmacology ; Male ; Medicine ; Medicine &amp; Public Health ; Myopia ; Myopia - surgery ; Ophthalmology ; Original Paper ; Pain ; Pain, Postoperative - therapy ; Photorefractive Keratectomy - adverse effects ; Photorefractivity ; Postoperative period ; Prospective Studies ; Signs and symptoms ; Silicones ; Silicones - pharmacology ; Surgery ; Time Factors ; Young Adult</subject><ispartof>International ophthalmology, 2019-11, Vol.39 (11), p.2569-2574</ispartof><rights>Springer Nature B.V. 2019</rights><rights>International Ophthalmology is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-f350dfe9e685d9f0041e310dff28291742bf629e9877791d8749e6916b4b28573</citedby><cites>FETCH-LOGICAL-c375t-f350dfe9e685d9f0041e310dff28291742bf629e9877791d8749e6916b4b28573</cites><orcidid>0000-0003-3713-8815</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31065904$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yuksel, Erdem</creatorcontrib><creatorcontrib>Ozulken, Kemal</creatorcontrib><creatorcontrib>Uzel, Mehmet Murat</creatorcontrib><creatorcontrib>Taslipinar Uzel, Ayse Guzin</creatorcontrib><creatorcontrib>Aydoğan, Semih</creatorcontrib><title>Comparison of Samfilcon A and Lotrafilcon B silicone hydrogel bandage contact lenses in reducing postoperative pain and accelerating re-epithelialization after photorefractive keratectomy</title><title>International ophthalmology</title><addtitle>Int Ophthalmol</addtitle><addtitle>Int Ophthalmol</addtitle><description>Purpose To compare the efficacy of Samfilcon A and Lotrafilcon B bandage contact lenses after photorefractive keratectomy (PRK). Methods In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surgery and on postoperative days 1, 2 and 3. Slit biomicroscopy was performed to assess epithelial defect size in the postoperative examinations. The subjective evaluation of pain and visual symptoms was recorded on postoperative days 1, 2 and 3. Results Analysis was made of 68 eyes of 34 patients who fulfilled the criteria and had PRK for correction of low to moderate myopia/astigmatism. On postoperative days 1 and 2, pain and epiphora scores were significantly lower in eyes with Samfilcon A lens ( p  &lt; 0.001 for all), and on postoperative day 3, the differences were not significant ( p  = 0.414 and p  = 0.180, respectively). There was no significant difference between the two lenses in respect of the levels of photophobia. The difference in epithelial defect size was statistically lower in eyes with Samfilcon A lens compared to Lotrafilcon B on day 1 (16.89 mm 2 vs. 21.07 mm 2 ; p  = 0.003) and day 2 (1.49 mm 2 vs. 2.46 mm 2 ; p  &lt; 0.001). The difference was not significant on day 3. (0.05 mm 2 vs. 0.05 mm 2 ; p  = 1.000). 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Methods In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surgery and on postoperative days 1, 2 and 3. Slit biomicroscopy was performed to assess epithelial defect size in the postoperative examinations. The subjective evaluation of pain and visual symptoms was recorded on postoperative days 1, 2 and 3. Results Analysis was made of 68 eyes of 34 patients who fulfilled the criteria and had PRK for correction of low to moderate myopia/astigmatism. On postoperative days 1 and 2, pain and epiphora scores were significantly lower in eyes with Samfilcon A lens ( p  &lt; 0.001 for all), and on postoperative day 3, the differences were not significant ( p  = 0.414 and p  = 0.180, respectively). There was no significant difference between the two lenses in respect of the levels of photophobia. The difference in epithelial defect size was statistically lower in eyes with Samfilcon A lens compared to Lotrafilcon B on day 1 (16.89 mm 2 vs. 21.07 mm 2 ; p  = 0.003) and day 2 (1.49 mm 2 vs. 2.46 mm 2 ; p  &lt; 0.001). The difference was not significant on day 3. (0.05 mm 2 vs. 0.05 mm 2 ; p  = 1.000). Conclusions The Samfilcon A lens is superior to the Lotrafilcon B lens in reducing postoperative pain and accelerating re-epithelialization.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>31065904</pmid><doi>10.1007/s10792-019-01105-9</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-3713-8815</orcidid></addata></record>
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ispartof International ophthalmology, 2019-11, Vol.39 (11), p.2569-2574
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1573-2630
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source Springer Link
subjects Adolescent
Adult
Astigmatism
Bandages, Hydrocolloid
Contact lenses
Contact Lenses, Hydrophilic
Equipment Design
Eye
Eye (anatomy)
Female
Follow-Up Studies
Humans
Hydrogels
Hydrogels - pharmacology
Male
Medicine
Medicine & Public Health
Myopia
Myopia - surgery
Ophthalmology
Original Paper
Pain
Pain, Postoperative - therapy
Photorefractive Keratectomy - adverse effects
Photorefractivity
Postoperative period
Prospective Studies
Signs and symptoms
Silicones
Silicones - pharmacology
Surgery
Time Factors
Young Adult
title Comparison of Samfilcon A and Lotrafilcon B silicone hydrogel bandage contact lenses in reducing postoperative pain and accelerating re-epithelialization after photorefractive keratectomy
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