A systematic review and meta‐analysis to evaluate the efficacy of lumbar sympathectomy for plantar hyperhidrosis

• Published in: International journal of dermatology 2019-08, Vol.58 (8), p.982-986
• Main Authors: Lima, Sonia O., Santos, Rafael S., Moura, Amanda M. M., Neto, Edinaldo G., Andrade, Renata L. B., Valido, Arthur D., dos Santos, Vivian F., Mendonça, Ana K. R. H.
• Format: Article
• Language: English
• Subjects: Combined Modality Therapy - adverse effects; Combined Modality Therapy - methods; Female; Foot; Humans; Hyperhidrosis - diagnosis; Hyperhidrosis - psychology; Hyperhidrosis - therapy; Lumbosacral Plexus - drug effects; Lumbosacral Plexus - surgery; Male; Organ Sparing Treatments - adverse effects; Organ Sparing Treatments - methods; Postoperative Complications - diagnosis; Postoperative Complications - epidemiology; Postoperative Complications - etiology; Quality of Life; Sclerosing Solutions - administration & dosage; Sclerosing Solutions - adverse effects; Severity of Illness Index; Sex Factors; Sexual Dysfunction, Physiological - etiology; Sexual Dysfunction, Physiological - prevention & control; Sympathectomy - adverse effects; Sympathectomy - methods; Treatment Outcome
• ISSN: 0011-9059; 1365-4632
• DOI: 10.1111/ijd.14470

On July 25, 2017, we conducted an extensive database tracking to identify all studies published from January 1990 to July 2017. Screening updates were performed until December 2017. Results There were no deaths, and the resolution of symptoms of primary plantar hyperhidrosis (PPH) occurred in 92% of patients after mechanical sympathectomy. A total of 177 patients (44%) were reported to have mild to severe compensatory sweating after a mean 6 months follow‐up. The preservation of L2 did not interfere with the primary outcome, and it is possible to perform lumbar sympathectomy in men with L2 preservation, achieving satisfactory cure results of PPH, minimizing the risk of sexual dysfunction. There were no deaths, and the resolution of symptoms of PPH occurred in 10% of patients after chemical sympathicolysis after a mean 6 months follow‐up. A total of 13 patients (12.5%) were reported to have mild to severe compensatory sweating using the same technique. Conclusion The mechanical lumbar sympathectomy is effective and safe and improves quality of life, evaluated by the high symptom resolution of PPH and low rate of complications. The chemical sympathicolysis in the immediate postoperative period presented satisfactory results; however, it was shown to be significantly less effective than the mechanical approach in a follow‐up of at least 6 months.