Outcomes of multi-gestational pregnancies affected by esophageal atresia – tracheoesophageal fistula

Contemporary outcomes of infants with esophageal atresia with or without tracheoesophageal fistula (EA/TEF) from multi-gestational pregnancies compared to those of singleton pregnancies have not been reported. A single-center retrospective review of EA/TEF patients born from 1999 to 2013 was perform...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pediatric surgery 2019-10, Vol.54 (10), p.2080-2083
Main Authors: Forster, Corey, Zamiara, Paul, Lapidus-Krol, Eveline, Chiang, Monping, Scaini, Vikki, Haliburton, Beth, Moore, Aideen M., Marcon, Margaret A., Chiu, Priscilla P.L.
Format: Article
Language:English
Subjects:
Congenital anomalies
Esophageal atresia
Esophageal Atresia - epidemiology
Esophageal Atresia - mortality
Esophageal Atresia - surgery
Female
Gestational Age
Humans
Infant, Newborn
Infant, Newborn, Diseases - epidemiology
Infant, Newborn, Diseases - mortality
Infant, Newborn, Diseases - surgery
Morbidity
Mortality
Pregnancy
Pregnancy, Multiple - statistics & numerical data
Retrospective Studies
Singleton pregnancy
Tracheoesophageal Fistula - epidemiology
Tracheoesophageal Fistula - mortality
Tracheoesophageal Fistula - surgery
Treatment Outcome
Twin pregnancy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Contemporary outcomes of infants with esophageal atresia with or without tracheoesophageal fistula (EA/TEF) from multi-gestational pregnancies compared to those of singleton pregnancies have not been reported. A single-center retrospective review of EA/TEF patients born from 1999 to 2013 was performed. Patient demographics, gestational age (GA), birth weight, associated anomalies, requirement for gastrostomy tube and mortality were reviewed. Singleton EA/TEF patients outnumbered those from multi-gestational pregnancies nearly 10:1 (214 vs 22 patients). EA/TEF patients from multi-gestational pregnancies were more likely to be premature (77% vs. 32%), have lower birth weight (mean 1766 g vs. 2695 g), have associated duodenal atresia (18% vs. 6%) and require gastrostomy tube (41% vs. 33%) for feeding challenges compared to EA/TEF singletons. Mortality was also significantly greater for multi-gestational EA/TEF patients compared to singleton EA/TEF patients (18% vs. 6%). Conclusion: EA/TEF infants from multi-gestational pregnancies have greater clinical complexity and mortality than singleton EA/TEF patients. Parents of EA/TEF multi-gestational infants should be appropriately counseled and supported.
ISSN:0022-3468
1531-5037
DOI:10.1016/j.jpedsurg.2019.04.026