Recent developments and comparison of transformation strategies for organic halides to aldehydes and ketones

Aldehydes and ketones are parts of millions of compounds and are important classes of chemicals which serve as important precursors for the synthesis of library of compounds. For the synthesis of aldehydes and ketones, one impressive approach to date, because of its excellent selectivity, high yield...

Full description

Saved in:
Bibliographic Details
Published in:Molecular diversity 2020-05, Vol.24 (2), p.571-592
Main Authors: Faisal, Muhammad, Saeed, Aamer, Shahzad, Danish, Dar, Parsa, Larik, Fayaz Ali
Format: Article
Language:English
Subjects:
Aldehydes
Aldehydes - chemical synthesis
Biochemistry
Biomedical and Life Sciences
Halides
Ketones
Ketones - chemical synthesis
Life Sciences
Organic Chemistry
Oxidation
Pharmacy
Polymer Sciences
Short Review
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aldehydes and ketones are parts of millions of compounds and are important classes of chemicals which serve as important precursors for the synthesis of library of compounds. For the synthesis of aldehydes and ketones, one impressive approach to date, because of its excellent selectivity, high yield and stability toward over-reduction and over-oxidation, is the oxidation of organic halides (viz. aliphatic and benzyl halides). The current review covers the conventional and eco-friendly transformational approaches, from 2000 to date, toward synthesis of aldehydes and ketones from organic halides, including mechanistic studies, comparison of different transformational strategies and discussion on scope and cons and pros of each transformational approach. The review would be beneficial to get knowledge about recent synthesis techniques, select finest synthetic approach, develop further new transformational methodologies and improve current transformational approaches. Graphical abstract
ISSN:1381-1991
1573-501X
DOI:10.1007/s11030-019-09956-1