Interrelational changes in the epidemiology and clinical features of nontuberculous mycobacterial pulmonary disease and tuberculosis in a referral hospital in Japan

The incidence of nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasing, while that of tuberculosis (TB) is decreasing in many industrialized countries, including Japan. However, the long-term evaluation of clinico-epidemiological features of NTM-PD in relation to TB are limited. We a...

Full description

Saved in:
Bibliographic Details
Published in:Respiratory medicine 2019-06, Vol.152, p.74-80
Main Authors: Furuuchi, Koji, Morimoto, Kozo, Yoshiyama, Takashi, Tanaka, Yoshiaki, Fujiwara, Keiji, Okumura, Masao, Izumi, Kiyohiko, Shiraishi, Yuji, Mitarai, Satoshi, Ogata, Hideo, Kurashima, Atsuyuki, Yoshimori, Kozo, Ohta, Ken, Goto, Hajime, Sasaki, Yuka
Format: Article
Language:English
Subjects:
Abscesses
Adult
Age
Age composition
Age Distribution
Aged
Aged, 80 and over
Aging
Bronchiectasis - pathology
Clinical features
Epidemiology
Female
Females
Humans
Incidence
Infectious diseases
Japan
Japan - epidemiology
Lung diseases
Lung Diseases - epidemiology
Lung Diseases - microbiology
Male
Males
Mens health
Middle Aged
Mycobacterium abscessus - isolation & purification
Mycobacterium avium
Mycobacterium avium Complex - isolation & purification
Mycobacterium avium-intracellulare Infection - diagnostic imaging
Mycobacterium avium-intracellulare Infection - epidemiology
Mycobacterium avium-intracellulare Infection - microbiology
Mycobacterium avium-intracellulare Infection - pathology
Mycobacterium Infections, Nontuberculous - diagnostic imaging
Mycobacterium Infections, Nontuberculous - epidemiology
Mycobacterium Infections, Nontuberculous - microbiology
Mycobacterium Infections, Nontuberculous - pathology
Mycobacterium kansasii - isolation & purification
Nontuberculous mycobacteria
Nontuberculous Mycobacteria - isolation & purification
Patients
Referral and Consultation
Thorax
Trends
Tuberculosis
Tuberculosis, Pulmonary - diagnostic imaging
Tuberculosis, Pulmonary - epidemiology
Tuberculosis, Pulmonary - microbiology
Tuberculosis, Pulmonary - pathology
Womens health
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The incidence of nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasing, while that of tuberculosis (TB) is decreasing in many industrialized countries, including Japan. However, the long-term evaluation of clinico-epidemiological features of NTM-PD in relation to TB are limited. We aimed to clarify the long-term changes in the epidemiology and clinical features of NTM-PD in relation to those of TB at a nationally-designated TB center in Japan. We reviewed all mycobacterial examination records at Fukujuji Hospital between 2006 and 2016. Cases of NTM-PD were defined according to the 2007 American Thoracic Society/Infectious Disease Society of America microbiologic criteria. The current characteristics of Mycobacterium avium complex pulmonary disease (MAC-PD) were compared with those in the 1980s and circa 2000. We identified a total of 3,546 pulmonary TB cases and 2,155 NTM-PD cases. While the annual number of incident pulmonary TB cases remained stable over the study period (P = 0.59), that of NTM-PD cases increased significantly from 165 to 278 (P 
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2019.05.001