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Recurrence After Resection for Intraductal Papillary Neoplasm of Bile Duct (IPNB) According to Tumor Location

Background No studies have yet analyzed the characteristics of recurrence after resection for intraductal papillary neoplasm of bile duct (IPNB) based on tumor location. We analyzed the patterns, timing, and risk factors for recurrence. Methods From 1994 to 2014, data from 103 patients who were diag...

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Published in:Journal of gastrointestinal surgery 2020-04, Vol.24 (4), p.804-812
Main Authors: You, Yunghun, Choi, Seong Ho, Choi, Dong Wook, Heo, Jin Seok, Han, In Woong, Jang, Kee-Taek, Han, Sunjong
Format: Article
Language:English
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Summary:Background No studies have yet analyzed the characteristics of recurrence after resection for intraductal papillary neoplasm of bile duct (IPNB) based on tumor location. We analyzed the patterns, timing, and risk factors for recurrence. Methods From 1994 to 2014, data from 103 patients who were diagnosed with IPNB were retrospectively reviewed. Among these, 44 were extrahepatic IPNB (E-IPNB) and 59 were intrahepatic IPNB (I-IPNB). Results CK20, pancreaticobiliary type, tumor invasion beyond ductal wall, tumor invasion to adjacent organs, and invasive disease were more frequently found in E-IPNB than in I-IPNB (22.7 vs. 8.5%; p  = 0.043, 38.6 vs. 23.7%; p  = 0.050, 20.5 vs. 11.9%; p  
ISSN:1091-255X
1873-4626
DOI:10.1007/s11605-019-04235-8