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Lysine-specific demethylase 1 accelerates oncogenesis in p53 heterozygous mice via transcriptional repression of the residual Trp53 allele

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Bibliographic Details
Published in:	Leukemia research 2019-07, Vol.82, p.29-32
Main Authors:	Wada, Taeko, Kikuchi, Jiro, Koyama, Daisuke, Honda, Hiroaki, Furukawa, Yusuke
Format:	Article
Language:	English
Subjects:	Alleles Animals Bone Marrow - metabolism Bone Marrow - pathology Carcinogenesis - genetics Carcinogenesis - metabolism Carcinogenesis - pathology Carcinoma - genetics Carcinoma - metabolism Carcinoma - mortality Carcinoma - pathology Disease Models, Animal Gene Expression Regulation, Neoplastic Haploinsufficiency Heterozygote Histone Demethylases - genetics Histone Demethylases - metabolism Histones - genetics Histones - metabolism Humans Liver - metabolism Liver - pathology Lymphoma - genetics Lymphoma - metabolism Lymphoma - mortality Lymphoma - pathology Mice Mice, Inbred C57BL Mice, Knockout Sarcoma - genetics Sarcoma - metabolism Sarcoma - mortality Sarcoma - pathology Signal Transduction Spleen - metabolism Spleen - pathology Survival Analysis Thymus Gland - metabolism Thymus Gland - pathology Transcription, Genetic Tumor Suppressor Protein p53 - deficiency Tumor Suppressor Protein p53 - genetics
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