Follicle-stimulating hormone (FSHβ) gene polymorphisms and associations with reproductive traits in Rex rabbits

Follicle-stimulating hormone (FSH) stimulates granulosa cell proliferation and controls the development and maturation of oocytes. In this study with Rex rabbit, there was exploration of the relationships between reproductive traits and SNPs and haplotypes of FSHβ, and tested whether FSHβ SNPs would...

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Bibliographic Details
Published in:Animal reproduction science 2019-08, Vol.207, p.36-43
Main Authors: Niu, Xiaoyan, Martin, Graeme B., Liu, Wenzhong, Henryon, Mark A., Ren, Keliang
Format: Article
Language:English
Subjects:
Animals
Association
Female
Follicle Stimulating Hormone, beta Subunit - genetics
Follicle-stimulating hormone
Genetic Association Studies - veterinary
Polymorphism, Single Nucleotide
Pregnancy
Quantitative Trait, Heritable
Rabbits - genetics
Rabbits - physiology
Reproduction
Reproduction - genetics
Rex rabbit
Selective Breeding - genetics
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Summary:Follicle-stimulating hormone (FSH) stimulates granulosa cell proliferation and controls the development and maturation of oocytes. In this study with Rex rabbit, there was exploration of the relationships between reproductive traits and SNPs and haplotypes of FSHβ, and tested whether FSHβ SNPs would segregate between two lines, using 70 females from the White line and 100 females from the Beaver line. Three SNPs (FSH2, FSH30, FSH31) in exon1 and exon3 of FSHβ were strongly associated with reproductive traits in the combined population. For FSH2, the GG variant was associated with greater (P 
ISSN:0378-4320
1873-2232
DOI:10.1016/j.anireprosci.2019.05.013