Low serum magnesium and 1‐year mortality in alcohol withdrawal syndrome

Background In 2014, the WHO reported that 6% of all deaths were attributable to excess alcohol consumption. The aim of the present study was to examine the relationship between serum magnesium concentrations and mortality in patients with alcohol withdrawal syndrome (AWS). Materials and methods A re...

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Bibliographic Details
Published in:European journal of clinical investigation 2019-09, Vol.49 (9), p.e13152-n/a
Main Authors: Maguire, Donogh, Ross, David P., Talwar, Dinesh, Forrest, Ewan, Naz Abbasi, Hina, Leach, John‐Paul, Woods, Marylynne, Zhu, Luke Y., Dickson, Scott, Kwok, Tong, Waterson, Isla, Benson, George, Scally, Benjamin, Young, David, McMillan, Donald C.
Format: Article
Language:English
Subjects:
Age
Albumins
Alcohol
Alcohol withdrawal
Alcoholic beverages
Alkaline phosphatase
Benzodiazepines
Bilirubin
Death
Inhibitors
Magnesium
Mortality
Platelets
Prophylaxis
Proton pump inhibitors
Regression analysis
Sodium
Thiamine
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Summary:Background In 2014, the WHO reported that 6% of all deaths were attributable to excess alcohol consumption. The aim of the present study was to examine the relationship between serum magnesium concentrations and mortality in patients with alcohol withdrawal syndrome (AWS). Materials and methods A retrospective review of 700 patients with documented evidence of previous AWS indicating a requirement for benzodiazepine prophylaxis or evidence of alcohol withdrawal syndrome between November 2014 and March 2015. Results Of 380 patients included in the sample analysis, 64 (17%) were dead at 1 year following the time of treatment for AWS. The majority of patients had been prescribed thiamine (77%) and a proton pump inhibitor (66%). In contrast, the majority of patients had low circulating magnesium concentrations (
ISSN:0014-2972
1365-2362
DOI:10.1111/eci.13152