Comparison of fractional flow reserve and angiographic characteristics after balloon angioplasty in de novo coronary lesions

Lesion characteristics determined by angiography after balloon angioplasty such as residual dimeter stenosis (DS) or dissection type has been used to determine the treatment method of drug-coated balloon (DCB) or metal stent for de novo coronary lesions. The aim of this study is to identify angiogra...

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Bibliographic Details
Published in:The International Journal of Cardiovascular Imaging 2019-11, Vol.35 (11), p.1945-1954
Main Authors: Chung, Ju-Hyun, Lee, Kyung Eun, Her, Ae-Young, Lee, Joo Myung, Doh, Joon-Hyung, Nam, Chang-Wook, Koo, Bon-Kwon, Shin, Eun-Seok
Format: Article
Language:English
Subjects:
Aged
Angiography
Angioplasty
Angioplasty, Balloon, Coronary - adverse effects
Angioplasty, Balloon, Coronary - instrumentation
Balloon treatment
Cardiac Catheterization
Cardiac Catheters
Cardiac Imaging
Cardiology
Coated Materials, Biocompatible
Coronary Angiography
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - physiopathology
Coronary Artery Disease - therapy
Coronary Stenosis - diagnostic imaging
Coronary Stenosis - physiopathology
Coronary Stenosis - therapy
Coronary Vessels - diagnostic imaging
Coronary Vessels - physiopathology
Dissection
Female
Fractional Flow Reserve, Myocardial
Humans
Imaging
Implants
Lesions
Male
Medical imaging
Medicine
Medicine & Public Health
Middle Aged
Original Paper
Parameters
Predictive Value of Tests
Prospective Studies
Radiology
Registries
Stenosis
Stents
Surgical implants
Treatment Outcome
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Summary:Lesion characteristics determined by angiography after balloon angioplasty such as residual dimeter stenosis (DS) or dissection type has been used to determine the treatment method of drug-coated balloon (DCB) or metal stent for de novo coronary lesions. The aim of this study is to identify angiographic and functional mismatch using residual DS, dissection type and fractional flow reserve (FFR). Baseline and post-balloon parameters were obtained from 151 patients with 167 lesions. Angiographically significant parameters after balloon angioplasty are residual DS > 30% or dissection type C or more. Post-balloon FFR cutoff value of 0.75 was used to define functionally significant lesions. The weak correlation was found between residual DS and post-balloon FFR (r =  − 0.317, p  30% and post-balloon FFR ≥ 0.75) and 7.1% of reverse mismatch population (residual DS ≤ 30% and post-balloon FFR 
ISSN:1569-5794
1573-0743
1875-8312
DOI:10.1007/s10554-019-01649-y