Adipose‐Specific Expression, Developmental and Nutritional Regulation of the Gene‐Encoding Retinol‐Binding Protein 7 in Pigs

Modulation of expression of adipose tissue‐specific transcripts has been known to regulate adipogenesis and lipid metabolism. Recently, adipose‐specific expression patterns and developmental regulation of the gene‐encoding retinol‐binding protein 7 (RBP7) was identified. However, its expression in a...

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Bibliographic Details
Published in:Lipids 2019-06, Vol.54 (6-7), p.359-367
Main Authors: Ahn, Jinsoo, Suh, Yeunsu, Lee, Kichoon
Format: Article
Language:English
Subjects:
Adipose‐specific expression
Adiposity - genetics
Animals
Fasting
Fat cell
Pigs
Porcine
Retinol-Binding Proteins - genetics
Retinol-Binding Proteins - metabolism
Retinol‐binding protein 7 (RBP7)
Swine - genetics
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Summary:Modulation of expression of adipose tissue‐specific transcripts has been known to regulate adipogenesis and lipid metabolism. Recently, adipose‐specific expression patterns and developmental regulation of the gene‐encoding retinol‐binding protein 7 (RBP7) was identified. However, its expression in adipose tissue of the porcine species has yet to be explored. In this study, adipose tissue‐specific expression of porcine RBP7 was identified and conservation of the fatty acid‐binding domains and evolutionary relationship of the RBP7 gene were verified comparatively across mammalian species. Our in vitro and in vivo analysis of gene expression revealed that RBP7 expression was significantly high in fat cell fraction compared to stromal vascular cells (p 
ISSN:0024-4201
1558-9307
DOI:10.1002/lipd.12170