Root surface demineralization by citric acid/tetracycline gel and aPDT associated to subepithelial connective tissue graft improves root coverage outcomes. A 12-month preliminary randomized clinical trial

Root conditioners are used to promote root surface biomodification to increase the success rate of root coverage. Citric acid and tetracycline are commonly used. There is recent indication for using antimicrobial photodynamic therapy (aPDT) with this purpose. The aim of this study is to evaluate the...

Full description

Saved in:
Bibliographic Details
Published in:Journal of photochemistry and photobiology. B, Biology Biology, 2019-08, Vol.197, p.111528-111528, Article 111528
Main Authors: Damante, Carla Andreotti, Karam, Paula Stephania Brandão Hage, Ferreira, Rafael, Rezende, Maria Lúcia Rubo, Greghi, Sebastião Luiz Aguiar, Sant'Ana, Adriana Campos Passanezi, Zangrando, Mariana Schutzer Ragghianti
Format: Article
Language:English
Subjects:
Acids
Citric acid
Clinical trials
Connective tissues
Demineralization
Demineralizing
Dentin
Depth perception
Gingival recession
Hypersensitivity
Lasers
Patients
Photochemotherapy
Photodynamic therapy
Planing
Recession
Reduction
Scaling
Skin & tissue grafts
Soft tissues
Tissue grafting
Tissues
Toluidine
Toluidine blue
Tooth demineralization
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Root conditioners are used to promote root surface biomodification to increase the success rate of root coverage. Citric acid and tetracycline are commonly used. There is recent indication for using antimicrobial photodynamic therapy (aPDT) with this purpose. The aim of this study is to evaluate the effects of citric acid/tetracycline gel and aPDT in root coverage of gingival recessions using subepithelial connective tissue graft. This parallel, double-blinded clinical trial enrolled 17 patients (60 recession defects; 20/group). Experimental groups were: Control group (SRP) - scaling and root planing only; Citric acid/tetracycline gel (CAT) group - SRP plus citric acid/tetracycline gel; aPDT - SRP, toluidine blue O (100 μl/ml) and red laser. At baseline and after 3, 6 and 12 months, the clinical parameters were evaluated: recession depth (RD), percentage of root coverage (%RC), keratinized tissue width (KTW), soft tissue thickness (STT), probing depth (PD), clinical attachment level (CAL), dentin hypersensitivity (HYPER) and esthetic perception by patient (EST). CAT group presented reduction in PD, CAL, RD, increase in KTW and STT, higher %RC (81.6%) and better esthetic in relation to SRP group (p 
ISSN:1011-1344
1873-2682
DOI:10.1016/j.jphotobiol.2019.111528