Association of elevated serum triglyceride levels with a more severe course of acute pancreatitis: Cohort analysis of 1457 patients

• Published in: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2019-07, Vol.19 (5), p.623-629
• Main Authors: Pascual, Isabel, Sanahuja, Ana, García, Natalia, Vázquez, Paola, Moreno, Oswaldo, Tosca, Joan, Peña, Andrés, Garayoa, Ana, Lluch, Paloma, Mora, Francisco
• Format: Article
• Language: English
• Subjects: Acute Disease; Acute pancreatitis; Adolescent; Adult; Age; Aged; Aged, 80 and over; Body mass index; Cohort analysis; Cohort Studies; Comorbidity; Data collection; Diabetes; Etiology; Failure; Female; Humans; Hypertriglyceridemia; Hypertriglyceridemia - blood; Hypertriglyceridemia - complications; Hypertriglyceridemia - mortality; Hypertriglyceridemic pancreatitis; Male; Metabolism; Middle Aged; Mortality; Multiple Organ Failure - etiology; Multiple Organ Failure - mortality; Multivariate analysis; Necrosis; Organ failure; Pancreas; Pancreas - pathology; Pancreatitis; Pancreatitis - blood; Pancreatitis - complications; Pancreatitis - mortality; Pancreatitis, Acute Necrotizing - blood; Patients; Prognosis; Retrospective Studies; Risk Factors; Severity; Treatment Outcome; Triglycerides; Triglycerides - blood; Variables; Young Adult
• ISSN: 1424-3903; 1424-3911
• DOI: 10.1016/j.pan.2019.06.006

Previous publications have reported an association between hypertriglyceridemia (HTG) and severity of acute pancreatitis, but this relationship remains somewhat controversial. To evaluate the outcome of acute pancreatitis according to serum triglyceride levels on admission. Retrospective analysis of prospectively collected data, which included all consecutive cases of acute pancreatitis admitted to a tertiary hospital (January 2002–December 2014). Acute pancreatitis patients were classified into 3 groups based on serum triglyceride levels (mg/dl) measured within 48 h from admission: normal triglycerides-mild HTG (