Valproate and female patients: Prescribing attitudes of Italian epileptologists

After the European Medicines Agency (EMA) warning on the use of valproate (VPA) in female patients, we explored the antiepileptic drug (AED) prescribing attitudes of Italian epileptologists with regard to sex and VPA use in patients with epilepsy. A specifically designed 30-item questionnaire was di...

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Bibliographic Details
Published in:Epilepsy & behavior 2019-08, Vol.97, p.182-186
Main Authors: Giuliano, Loretta, La Neve, Angela, Galimberti, Carlo Andrea, Aguglia, Umberto, Bilo, Leonilda, Ermio, Caterina, Monti, Giulia, Zambrelli, Elena, Zenesini, Corrado, Mostacci, Barbara
Format: Article
Language:English
Subjects:
Epilepsy
Female
Practice patterns
Valproate
Women
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Summary:After the European Medicines Agency (EMA) warning on the use of valproate (VPA) in female patients, we explored the antiepileptic drug (AED) prescribing attitudes of Italian epileptologists with regard to sex and VPA use in patients with epilepsy. A specifically designed 30-item questionnaire was distributed at the annual multicenter meeting of the Italian League Against Epilepsy (LICE), held in Rome on January 2018. One hundred and sixty-nine physicians answered the questionnaire. In females, VPA was significantly less prescribed as first-choice AED in childhood absence epilepsy (22% females vs 64% males, p 
ISSN:1525-5050
1525-5069
DOI:10.1016/j.yebeh.2019.05.024