Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study

The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at h...

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Bibliographic Details
Published in:Journal of critical care 2019-10, Vol.53, p.183-185
Main Authors: Mauri, Tommaso, Carlesso, Eleonora, Spinelli, Elena, Turrini, Cecilia, Corte, Francesca Dalla, Russo, Riccarda, Ricard, Jean-Damien, Pesenti, Antonio, Roca, Oriol, Grasselli, Giacomo
Format: Article
Language:English
Subjects:
Accuracy
Acute hypoxemic respiratory failure
Aged
Blood Gas Analysis
Critical care
Cross-Over Studies
Electrical impedance tomography
Female
Gas flow
Hemodynamics
Humans
Hypoxia - physiopathology
Hypoxia - prevention & control
Intubation
Male
Middle Aged
Monitoring
Nasal high flow
Noninvasive Ventilation - methods
Nose
Oxygen Inhalation Therapy
Prospective Studies
Respiratory Insufficiency - etiology
Respiratory Insufficiency - physiopathology
Respiratory Insufficiency - therapy
Respiratory Rate
Success
Ventilators
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Summary:The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at higher flow (n = 40) showed worse baseline oxygenation, higher respiratory rate and lower ROX index in comparison to patients with unchanged or decreased ROX index values (n = 17). The ROX index variation between flows was correlated with the change in end expiratory lung volume. Set flow rate during NHF might impact the ROX index value.
ISSN:0883-9441
1557-8615
DOI:10.1016/j.jcrc.2019.06.020