Looking past the appearance: a comprehensive description of the clinical contribution of poor-quality blastocysts to increase live birth rates during cycles with aneuploidy testing

Which are the clinical benefits and risks of including poor-quality blastocysts (PQBs) in the cohort of biopsied embryos during a cycle with preimplantation genetic testing for aneuploidies (PGT-A)? PQBs show a worse prognosis with respect to sibling non-PQBs, but their clinical use allows an overal...

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Bibliographic Details
Published in:Human reproduction (Oxford) 2019-07, Vol.34 (7), p.1206-1214
Main Authors: Cimadomo, Danilo, Soscia, Daria, Vaiarelli, Alberto, Maggiulli, Roberta, Capalbo, Antonio, Ubaldi, Filippo Maria, Rienzi, Laura
Format: Article
Language:English
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Summary:Which are the clinical benefits and risks of including poor-quality blastocysts (PQBs) in the cohort of biopsied embryos during a cycle with preimplantation genetic testing for aneuploidies (PGT-A)? PQBs show a worse prognosis with respect to sibling non-PQBs, but their clinical use allows an overall 2.6% increase in the number of live births (LBs) achievable after PGT-A. PQBs (
ISSN:0268-1161
1460-2350
DOI:10.1093/humrep/dez078