Transcatheter Aortic Valve-in-Valve Replacement for Degenerated Stentless Bioprosthetic Aortic Valves: Results of a Multicenter Retrospective Analysis

The purpose of this study was to evaluate the safety and efficacy of valve-in-valve (ViV) transcatheter aortic valve replacement (TAVR) for stentless bioprosthetic aortic valves (SBAVs) and to identify predictors of adverse events. ViV TAVR in SBAVs is associated with unique technical challenges and...

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Published in:JACC. Cardiovascular interventions 2019-07, Vol.12 (13), p.1217-1226
Main Authors: Miller, Matthew, Snyder, Mandy, Horne, Benjamin D, Harkness, James R, Doty, John R, Miner, Edward C, Jones, Kent W, O'Neal, Kelly R, Reid, Bruce B, Caine, William T, Clayson, Stephen E, Lindley, Eric, Gardner, Blake, Connors, Rafe C, Bowles, B Jason, Whisenant, Brian K
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container_issue 13
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container_title JACC. Cardiovascular interventions
container_volume 12
creator Miller, Matthew
Snyder, Mandy
Horne, Benjamin D
Harkness, James R
Doty, John R
Miner, Edward C
Jones, Kent W
O'Neal, Kelly R
Reid, Bruce B
Caine, William T
Clayson, Stephen E
Lindley, Eric
Gardner, Blake
Connors, Rafe C
Bowles, B Jason
Whisenant, Brian K
description The purpose of this study was to evaluate the safety and efficacy of valve-in-valve (ViV) transcatheter aortic valve replacement (TAVR) for stentless bioprosthetic aortic valves (SBAVs) and to identify predictors of adverse events. ViV TAVR in SBAVs is associated with unique technical challenges and risks. Clinical records and computer tomographic scans were retrospectively reviewed for procedural complications, predictors of coronary obstruction, mortality, and echocardiographic results. Among 66 SBAV patients undergoing ViV TAVR, mortality was 2 of 66 patients (3.0%) at 30 days and 5 of 52 patients (9.6%) at 1 year. At 1 year, left ventricular end-systolic dimension was decreased versus baseline (median [interquartile range (IQR)]: 3.0 [2.6 to 3.6] cm vs. 3.7 [3.2 to 4.4] cm; p 
doi_str_mv 10.1016/j.jcin.2019.05.022
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title Transcatheter Aortic Valve-in-Valve Replacement for Degenerated Stentless Bioprosthetic Aortic Valves: Results of a Multicenter Retrospective Analysis
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