Prepregnancy care in women with type 1 diabetes improves HbA1c and glucose variability without worsening hypoglycaemia time and awareness: Glycaemic variability during prepregnancy care

AIMSTo evaluate the impact of a prepregnancy care (PPC) programme, beyond HbA1c, on hypoglycaemia awareness and glycaemic variability (GV). METHODSProspective pilot study. We selected women with Type 1 diabetes who initiated a PPC programme with normal hypoglycaemia awareness (n = 24). Hypoglycaemia...

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Published in:Diabetes research and clinical practice 2019-08, Vol.154, p.75-81
Main Authors: Perea, Verónica, Giménez, Marga, Amor, Antonio J, Bellart, Jordi, Conget, Ignacio, Vinagre, Irene
Format: Article
Language:English
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Summary:AIMSTo evaluate the impact of a prepregnancy care (PPC) programme, beyond HbA1c, on hypoglycaemia awareness and glycaemic variability (GV). METHODSProspective pilot study. We selected women with Type 1 diabetes who initiated a PPC programme with normal hypoglycaemia awareness (n = 24). Hypoglycaemia awareness, hypoglycaemic events and GV derived from masked-continuous glucose monitoring were evaluated in the first visit and within 2 weeks after pregnancy confirmation. RESULTSThe duration was 16.5 ± 13.0 months. HbA1c significantly decreased (-0.8 ± 0.7; p 
ISSN:1872-8227
DOI:10.1016/j.diabres.2019.06.015