Effect of external compression on femoral retrograde shear and microvascular oxygenation in exercise trained and recreationally active young men

Introduction Retrograde shear causes endothelial damage and is pro-atherogenic. The purpose of our study was to examine the impact of vascular remodeling from habitual exercise training on acute changes in retrograde shear and microvascular oxygenation (SMO 2 ) induced via 30 min of external compres...

Full description

Saved in:
Bibliographic Details
Published in:European journal of applied physiology 2019-08, Vol.119 (8), p.1809-1818
Main Authors: Lassalle, Patricia Pagan, Palamar, Adam J., DeBlois, Jacob P., Lefferts, Wesley K., Heffernan, Kevin S.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biomedical and Life Sciences
Biomedicine
Compression
Compression Bandages
Doppler effect
Endothelium, Vascular - physiology
Exercise
Femoral Artery - physiology
Femur
Flow velocity
Hemodynamics
Human Physiology
Humans
Infrared spectroscopy
Male
Microvasculature
Microvessels - physiology
Muscle, Skeletal - blood supply
Muscle, Skeletal - physiology
Occupational Medicine/Industrial Medicine
Original Article
Oxygen Consumption
Oxygenation
Reperfusion
Sports Medicine
Ultrasound
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction Retrograde shear causes endothelial damage and is pro-atherogenic. The purpose of our study was to examine the impact of vascular remodeling from habitual exercise training on acute changes in retrograde shear and microvascular oxygenation (SMO 2 ) induced via 30 min of external compression. Methods Participants included 11 exercise trained (ET) men (Division I track athletes; age 20 ± 3 years) and 18 recreationally active (RA) men (age 23 ± 5 years). Near-infrared spectroscopy (NIRS) was used to measure vastus medialis SMO 2 . Doppler-ultrasound was used to assess SFA intima-media thickness, diameter and flow velocity to derive retrograde shear. Vascular measures were made at baseline (BASELINE), during a sham condition (calf compression to 5 mmHg, SHAM) and during the experimental condition (calf compression to 60 mmHg, EXP). Results Compared to RA, ET had larger SFA diameters (0.66 ± 0.06 vs 0.58 ± 0.06 cm, p  
ISSN:1439-6319
1439-6327
DOI:10.1007/s00421-019-04170-1