Seasonal Variations In The Level Of Mutagenicity: An Assessment Of Respirable Particulate Matter In Rio De Janeiro, Brazil

Respirable particles (PM2.5) can become associated with organic matter containing several compounds such as polycyclic aromatic hydrocarbons (PAHs). Many PAHs have been identified as cancer-inducing chemicals. The mutagenicity of airborne particles is generally associated with PAHs, but recent revie...

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Bibliographic Details
Published in:WIT Transactions on Ecology and the Environment 2014-01, Vol.183, p.87
Main Authors: Rainho, C R, Correa, S M, Mazzei, J L, Aiub, C A F, Felzenszwalb, I
Format: Article
Language:English
Subjects:
Air pollution
Amines
Aromatic compounds
Climatic conditions
Exhaust gases
Exhausts
Gas chromatography
Gasoline
Ketones
Levels
Metabolic activation
Metabolic rate
Metabolism
Mutagenicity
Mutagens
Nitrogen dioxide
Organic chemistry
Organic matter
Particulate matter
Polycyclic aromatic hydrocarbons
Salmonella
Salmonella typhimurium
Seasonal variations
Spectrometry
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Summary:Respirable particles (PM2.5) can become associated with organic matter containing several compounds such as polycyclic aromatic hydrocarbons (PAHs). Many PAHs have been identified as cancer-inducing chemicals. The mutagenicity of airborne particles is generally associated with PAHs, but recent reviews show that PAHs may not be the predominant mutagens in atmospheric pollution, and that nitroaromatic compounds, aromatic amines and aromatic ketones, often found in moderately polar or highly polar organic fractions, are potent mutagens. Nitro-polycyclicaromatics (nitro-PAHs) are persistent environmental mutagens and can be found in airborne suspended particles from direct sources such as diesel and gasoline exhausts, or may be products of atmospheric reactions in the presence of NO2 and NO3 radicals. In the present work we compared PAH levels and mutagenicity using gas chromatography spectrometry and the Salmonella/microsome assay on organic extracts of PM2.5 for Salmonella typhimurium strain TA98. The information generated in this study shows that different levels of PAHs and nitroderivatives, influenced by seasonal variations in climatic conditions, probably contribute to the detected airborne mutagenicity.
ISSN:1746-448X
1743-3541
DOI:10.2495/AIR140081