Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection: A real-world perspective and review of the literature

Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of 87% and 94% at 48 hours and 14 days, respectively. Response rates did not vary across pathogens. Our retrospective, observational findings su...

Full description

Saved in:
Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2019-11, Vol.95 (3), p.114856-114856, Article 114856
Main Authors: Babiker, Ahmed, Clarke, Lloyd, Doi, Yohei, Shields, Ryan K
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents - therapeutic use
CRE
Drug Resistance, Multiple, Bacterial - drug effects
ESBL
Female
Fosfomycin
Fosfomycin - therapeutic use
Humans
Male
Middle Aged
Retrospective Studies
Treatment Outcome
Urinary Tract Infections - drug therapy
Urinary Tract Infections - microbiology
UTI
VRE
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of 87% and 94% at 48 hours and 14 days, respectively. Response rates did not vary across pathogens. Our retrospective, observational findings support fosfomycin treatment against MDR pathogens causing UTIs.
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2019.06.008