The Adhesion of Human Dermal Fibroblasts on Anodized Nanotube-layered Titanium, Modified for Implantology Application

Anodization of titanium implants is accompanied by the formation of titanium oxide nanotubes improving osseointegration. An excessive fibroblast adhesion on the surface might lead to the formation of fibrous capsule resulting in implant rejection. In our research, we demonstrated that the adhesion a...

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Bibliographic Details
Published in:Doklady. Biological sciences 2019-05, Vol.486 (1), p.91-93
Main Authors: Fadeyev, F. A., Khrunyk, Yu. Ya, Belikov, S. V., Lugovets, D. V., Gubaeva, O. V., Karabanalov, M. S., Leontyev, S. L., Popov, A. A.
Format: Article
Language:English
Subjects:
Biocompatible Materials - chemistry
Biocompatible Materials - pharmacology
Biomedical and Life Sciences
Bone-Implant Interface
Cell Adhesion
Cell Biology
Cells, Cultured
Dental implants
Evolutionary Biology
Fibroblasts
Fibroblasts - drug effects
Fibroblasts - physiology
Humans
Life Sciences
Nanotubes
Nanotubes - chemistry
Osseointegration
Plant Sciences
Skin
Titanium
Titanium - chemistry
Titanium - pharmacology
Titanium oxide
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Summary:Anodization of titanium implants is accompanied by the formation of titanium oxide nanotubes improving osseointegration. An excessive fibroblast adhesion on the surface might lead to the formation of fibrous capsule resulting in implant rejection. In our research, we demonstrated that the adhesion activity of human dermal fibroblasts on anodized surface was not elevated, which is promising for the use of titanium with nanotube-layered surface for implantology.
ISSN:0012-4966
1608-3105
DOI:10.1134/S0012496619030013