Neonatal Gastrointestinal Stromal Tumor of the Sigmoid Colon: A Case Report and Review of Literature

ABSTACT Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms of the digestive tract. They are believed to originate from the interstitial cells of Cajal or their precursors. A 10-day-old boy presented with intestinal obstruction. He was operated upon and a mass was found...

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Bibliographic Details
Published in:Fetal and pediatric pathology 2020-03, Vol.39 (2), p.172-178
Main Authors: Kotb, Mostafa, Abdelaziz, Marwa, Beyaly, Marwa, Mekawy, Mohamed, Rashwan, Hayssam, Mashali, Nagwa
Format: Article
Language:English
Subjects:
Colon, Sigmoid - pathology
Gastrointestinal Stromal Tumors - congenital
Gastrointestinal Stromal Tumors - diagnosis
Gastrointestinal Stromal Tumors - pathology
Gastrointestinal Tract - pathology
Humans
Infant, Newborn
Intestinal Obstruction - congenital
Intestinal Obstruction - diagnosis
Intestinal Obstruction - pathology
Male
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Summary:ABSTACT Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms of the digestive tract. They are believed to originate from the interstitial cells of Cajal or their precursors. A 10-day-old boy presented with intestinal obstruction. He was operated upon and a mass was found at the sigmoid colon, which was resected and divided colostomy was performed. The diagnosis of neonatal GIST was confirmed by histologic and immunohistochemical studies. This is the ninth case of neonatal GIST that arose from the intestine and the first reported to arise from the sigmoid colon. Colonic GIST can occur in the neonatal age group.
ISSN:1551-3815
1551-3823
DOI:10.1080/15513815.2019.1641861