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Causes of oocyte vitrification and its value in assisted reproductive technology

To explore the causes of oocyte vitrification and its application in assisted reproduction. We retrospectively analyzed the data of 26 patients with 27 cycles of oocyte vitrification cryopreservation undergoing intracytoplasmic sperm injection (ICSI) and embryo transfer between January, 2008 and Oct...

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Published in:Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019-07, Vol.39 (7), p.766-771
Main Authors: Zhe, Jing, Zhang, Jun, Chen, Shiling, Zhang, Weiqing, Luo, Chen, Zhou, Xingyu, Chen, Xin, Qiu, Zhuolin, Li, Huixi, Wu, Xiaomin
Format: Article
Language:Chinese
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Summary:To explore the causes of oocyte vitrification and its application in assisted reproduction. We retrospectively analyzed the data of 26 patients with 27 cycles of oocyte vitrification cryopreservation undergoing intracytoplasmic sperm injection (ICSI) and embryo transfer between January, 2008 and October, 2018. The causes of oocyte vitrification and the outcomes of ICSI and clinical pregnancy were analyzed. The causes of oocytes vitrification included mainly azoospermia or severe spermatogenesis disorder of the husband, failure to obtain sperms from the husband, failure of the husband to be present on the day of oocyte retrieval and acute diseases of the husband to not allow sperm collection. A total of 274 oocytes were frozen in 27 oocyte retrieval cycles, and 217 eggs were thawed in 19 cycles with a survival rate of 81.11% (176/217). The normal fertilization rate, cleavage rate and high-quality embryo rate was 74.81% (98/131), 89.80% (88/98) and 36.73% (36/98), respectively. Fifteen patients underwent embryo
ISSN:1673-4254
DOI:10.12122/j.issn.1673-4254.2019.07.03