Common and uncommon features of nephrogenic adenoma revisited

Nephrogenic adenoma is a common diagnosis in urological pathology that may be challenging for general pathologists. Due to its polymorphic appearance under the microscope, some cases can be misdiagnosed as malignancy and then unnecessarily overtreated. Aside from the typical tubules, cysts and papil...

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Bibliographic Details
Published in:Pathology, research and practice research and practice, 2019-10, Vol.215 (10), p.152561-152561, Article 152561
Main Authors: Santi, Raffaella, Angulo, Javier C., Nesi, Gabriella, de Petris, Giovanni, Kuroda, Naoto, Hes, Ondrej, López, José I.
Format: Article
Language:English
Subjects:
Adenoma - pathology
Differential diagnosis
Humans
Immunohistochemistry
Kidney - pathology
Kidney Neoplasms - pathology
Morphology
Nephrogenic adenoma
Pseudotumor
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Summary:Nephrogenic adenoma is a common diagnosis in urological pathology that may be challenging for general pathologists. Due to its polymorphic appearance under the microscope, some cases can be misdiagnosed as malignancy and then unnecessarily overtreated. Aside from the typical tubules, cysts and papillae, nephrogenic adenoma may display a broad spectrum of histologic appearances and locations, some of them atypical or unexpected. These unusual and concerning features will have special consideration in this description. The goal of the review is to increase awareness of general pathologists of the varied histology of nephrogenic adenoma.
ISSN:0344-0338
1618-0631
DOI:10.1016/j.prp.2019.152561