Epicardial Application of Hydrogel with Amiodarone for Prevention of Postoperative Atrial Fibrillation in Patients After Coronary Artery Bypass Grafting

The objective of this study was to assess the safety and efficacy of local epicardial application of amiodarone-releasing hydrogel for prevention of postoperative atrial fibrillation (POAF) in patients after coronary artery bypass grafting. Patients were randomized into two groups: with the applicat...

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Bibliographic Details
Published in:Journal of cardiovascular translational research 2020-04, Vol.13 (2), p.191-198
Main Authors: Bockeria, O. L., Kanametov, T. N., Shvartz, V. A., Sokolskaya, M. A., Zhuginisov, D. Sh, Sanakoev, M. K., Bockeria, L. A.
Format: Article
Language:English
Subjects:
Biomedical Engineering and Bioengineering
Biomedicine
Cardiology
Human Genetics
Medicine
Medicine & Public Health
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Summary:The objective of this study was to assess the safety and efficacy of local epicardial application of amiodarone-releasing hydrogel for prevention of postoperative atrial fibrillation (POAF) in patients after coronary artery bypass grafting. Patients were randomized into two groups: with the application of amiodarone-releasing hydrogel and the control group. It included 60 patients (47 males, 13 females) (mean age of 62 ± 8.5). POAF incidence differences were statistically significant between two groups: in the study group, the POAF incidence was 3.3%, while in the control group, the POAF incidence was 37% ( p  
ISSN:1937-5387
1937-5395
DOI:10.1007/s12265-019-09905-1