Abbreviated Protocols versus Multiparametric MRI for Assessment of Extraprostatic Extension in Prostatic Carcinoma: A Multireader Study

Prostate multiparametric magnetic resonance imaging (mpMRI) is the reference imaging modality for extraprostatic extension of disease (EPE) assessment. We aimed to compare the diagnostic accuracy of different abbreviated MRI protocols to the standard prostate mpMRI in the identification of EPE of PC...

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Bibliographic Details
Published in:Anticancer research 2019-08, Vol.39 (8), p.4449-4454
Main Authors: Stanzione, Arnaldo, Ponsiglione, Andrea, Cuocolo, Renato, Cocozza, Sirio, Picchi, Stefano Giusto, Stilo, Salvatore, Persico, Francesco, Creta, Massimiliano, Longo, Nicola, Imbriaco, Massimo
Format: Article
Language:English
Subjects:
Aged
Carcinoma - complications
Carcinoma - diagnostic imaging
Carcinoma - pathology
Diagnostic systems
Humans
Identification methods
Magnetic Resonance Imaging
Male
Medical imaging
Middle Aged
NMR
Nuclear magnetic resonance
Prostate
Prostate - diagnostic imaging
Prostate - pathology
Prostate cancer
Prostatectomy
Prostatic Neoplasms - complications
Prostatic Neoplasms - diagnostic imaging
Prostatic Neoplasms - pathology
Radiology
Retrospective Studies
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Summary:Prostate multiparametric magnetic resonance imaging (mpMRI) is the reference imaging modality for extraprostatic extension of disease (EPE) assessment. We aimed to compare the diagnostic accuracy of different abbreviated MRI protocols to the standard prostate mpMRI in the identification of EPE of PCa. Fifty patients were retrospectively enrolled. Dual-pulse (dpMRI) and biparametric (bpMRI) abbreviated protocols were obtained from mpMRI. The performance of two experienced radiologists and two radiology residents was correlated with a reference standard and compared. Inter and intra-reader agreements were evaluated. All protocols were strongly correlated to the reference standard (p≤0.001). A significant difference was found between dpMRI and mpMRI (p=0.009), no differences emerged between bpMRI and mpMRI (p=0.27). All readers showed moderate agreement (ĸ=0.47, ĸ=0.50 and ĸ=0.53 for dpMRI, bpMRI and mpMRI, respectively). Intra-reader agreement was good (all ĸ values ≥0.70). Only bpMRI showed similar diagnostic performance to mpMRI, thus appearing as a feasible alternative to the standard protocol for EPE detection.
ISSN:0250-7005
1791-7530
DOI:10.21873/anticanres.13617