Cutaneous manifestations of angioimmunoblastic T-cell lymphoma

Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of non-Hodgkin lymphoma often accompanied by autoimmune and paraneoplastic phenomena. Up to 50% of patients with AITL present with skin manifestations. This case series highlights two cases of AITL presenting with unusual cutaneous findings: o...

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Bibliographic Details
Published in:Dermatology online journal 2019, Vol.25 (7)
Main Authors: Hoskins, Sidney, Moriarty, Natalie, White, Kevin, Kalus, Andrea, Shustov, Andrei, Shinohara, Michi M
Format: Article
Language:English
Subjects:
Fatal Outcome
Female
Humans
Immunoblastic Lymphadenopathy - pathology
Lymphoma
Lymphoma, T-Cell, Cutaneous - complications
Lymphoma, T-Cell, Cutaneous - pathology
Middle Aged
Paraneoplastic Syndromes - pathology
Skin - pathology
Skin Neoplasms - complications
Skin Neoplasms - pathology
Urticaria - etiology
Urticaria - pathology
Vasculitis - etiology
Vasculitis - pathology
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Description
Summary:Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of non-Hodgkin lymphoma often accompanied by autoimmune and paraneoplastic phenomena. Up to 50% of patients with AITL present with skin manifestations. This case series highlights two cases of AITL presenting with unusual cutaneous findings: one with a medium-vessel vasculitis and another with a chronic urticarial eruption. Clinicians should consider AITL in the differential diagnosis of vasculitis or urticaria refractory to standard treatment.
ISSN:1087-2108
1087-2108
DOI:10.5070/D3257044807