Activity of dalbavancin against gram-positive cocci isolated from skin and soft tissue infections in Poland

A total of 368 Gram-positive cocci from ABSSI were included in the study. S. aureus and S. pyogenes were susceptible to dalbavancin with MIC50 0.016 mg/L and MIC90 0.032 mg/L for MSSA and MIC50 0.032 mg/L and MIC90 0.047 mg/L for MRSA; MICs for S. pyogenes were ≤0.002–0.008 mg/L; for E. faecalis and...

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Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2019-12, Vol.95 (4), p.114881-114881, Article 114881
Main Authors: Stefaniuk, Elżbieta M., Dudek, Monika, Hryniewicz, Waleria
Format: Article
Language:English
Subjects:
Acute bacterial skin and soft tissue infections (ABSSI)
Anti-Bacterial Agents - pharmacology
Dalbavancin
Enterococci VanA and VanB
Epidemiological Monitoring
Gram-Positive Cocci - drug effects
Gram-Positive Cocci - isolation & purification
Humans
Methicillin-resistant Staphylococcus aureus (MRSA)
Methicillin-sensitive Staphylococcus aureus (MSSA)
Microbial Sensitivity Tests
Poland - epidemiology
Soft Tissue Infections - epidemiology
Soft Tissue Infections - microbiology
Streptococcus pyogenes
Teicoplanin - analogs & derivatives
Teicoplanin - pharmacology
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Summary:A total of 368 Gram-positive cocci from ABSSI were included in the study. S. aureus and S. pyogenes were susceptible to dalbavancin with MIC50 0.016 mg/L and MIC90 0.032 mg/L for MSSA and MIC50 0.032 mg/L and MIC90 0.047 mg/L for MRSA; MICs for S. pyogenes were ≤0.002–0.008 mg/L; for E. faecalis and E. faecium, ranging 0.016–0.12 mg/L and 0.012–≥32 mg/L, respectively; MICs for VRE were 0.032–0.125 mg/L.
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2019.114881