Chronic inflammatory demyelinating polyneuropathy with tongue fasciculation: A case report

[Display omitted] Chronic inflammatory demyelinating polyneuropathy is one of the immune-mediated polyneuropathies responsive to immunotherapy. Its usual clinical presentation is a chronic course of symmetric sensorimotor affectation of both proximal and distal extremities with signs of demyelinatio...

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Bibliographic Details
Published in:Journal of clinical neuroscience 2020-01, Vol.71, p.297-299
Main Authors: Roberto, Katrina T., Antonio, Athena Kate D., Fernandez, Marc Laurence L., Damian, Ludwig F.
Format: Article
Language:English
Subjects:
Chronic inflammatory demyelinating polyneuropathy
Hypoglossal neuropathy
Intravenous immunoglobulin
Nerve conduction studies
Tongue fasciculation
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Summary:[Display omitted] Chronic inflammatory demyelinating polyneuropathy is one of the immune-mediated polyneuropathies responsive to immunotherapy. Its usual clinical presentation is a chronic course of symmetric sensorimotor affectation of both proximal and distal extremities with signs of demyelination on electrophysiologic studies. Cranial nerve signs in this condition is not commonly encountered, particularly involvement of the hypoglossal nerve. To date, there are only three published cases of hypoglossal involvement in this condition. This case report presents a patient with tongue fasciculation, which is an uncommon finding in chronic inflammatory demyelinating polyneuropathy. This paper highlights the importance of considering chronic inflammatory demyelinating polyneuropathy in the differential diagnoses of a patient with tongue fasciculation as it has been found to be responsive to immunotherapy in comparison to other lower motor neuron syndromes.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2019.08.081