Mumps outbreak and MMR IgG surveillance as a predictor for immunity in military trainees

Highlights•Seven mumps cases occurred at a military training facility in 2017. •Mumps genotype G was the infectious genotype in all cases. •5/7 mumps cases were seropositive for Mumps IgG prior to infection. •30% of military contacts were seronegative to at least one MMR vaccine component. •No furth...

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Bibliographic Details
Published in:Vaccine 2019-09, Vol.37 (42), p.6139-6143
Main Authors: Nielsen, Lindsey E, Kelly, Devin C, Gyorffy, Janelle, Ager, Edward P, Markelz, Ana E
Format: Article
Language:English
Subjects:
Allergy and Immunology
Armed forces
Genotypes
IgG Titer
Immunity
Immunoglobulin G
Immunoglobulin M
Infections
Measles
Medical laboratories
Military training
MMR vaccine
Mumps
Orchitis
Outbreaks
Parotitis
Patients
Public health
Rubella
Serology
Vaccines
Viral infections
Viruses
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Summary:Highlights•Seven mumps cases occurred at a military training facility in 2017. •Mumps genotype G was the infectious genotype in all cases. •5/7 mumps cases were seropositive for Mumps IgG prior to infection. •30% of military contacts were seronegative to at least one MMR vaccine component. •No further cases presented 1-month after administration of a third MMR vaccine dose.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2019.08.054