Treatment of hepatitis C in two paediatric patients using sofosbuvir during haematopoietic stem cell transplantation

We report the first two paediatric cases of sofosbuvir treatment during high-intensity myeloablative conditioning and engraftment phases of haematopoietic stem cell transplantation. These reports highlight the safety of sofosbuvir during all phases of transplantation and the lack of interaction betw...

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Bibliographic Details
Published in:Antiviral therapy 2019-01, Vol.24 (8), p.603-607
Main Authors: Grasso, Antonio G, Sonzogni, Aurelio, Zanon, Davide, Maestro, Alessandra, Loiacono, Stefano, Maximova, Natalia
Format: Article
Language:English
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Summary:We report the first two paediatric cases of sofosbuvir treatment during high-intensity myeloablative conditioning and engraftment phases of haematopoietic stem cell transplantation. These reports highlight the safety of sofosbuvir during all phases of transplantation and the lack of interaction between sofosbuvir and alkylating or immunosuppressive agents.
ISSN:1359-6535
2040-2058
DOI:10.3851/IMP3332