Prevalence of self-reported sleep problems amongst adults with obstructive airway disease in the NHANES cohort in the United States

• Published in: Sleep & breathing 2020-09, Vol.24 (3), p.985-993
• Main Authors: Lal, Chitra, Kumbhare, Suchit, Strange, Charlie
• Format: Article
• Language: English
• Subjects: Allergic diseases; Apnea; Asthma; Body mass index; Chronic obstructive pulmonary disease; Demography; Dentistry; Diabetes mellitus; Internal Medicine; Leg; Lung diseases; Medicine; Medicine & Public Health; Memory; Neurology; Obstructive lung disease; Otorhinolaryngology; Pediatrics; Pneumology/Respiratory System; Regression analysis; Respiratory tract diseases; Sleep and wakefulness; Sleep Breathing Physiology and Disorders • Original Article; Sleep deprivation; Sleep disorders; Smoking
• ISSN: 1520-9512; 1522-1709
• DOI: 10.1007/s11325-019-01941-0

Rationale Sleep and respiratory problems are common in adults in the USA. However, sleep problems often remain undiagnosed in patients with obstructive airway diseases (OADs). This study was designed to examine the association between sleep problems and different categories of OAD amongst US adults. Methods We conducted an observational, cross-sectional study using a nationally representative sample of the US civilian non-institutionalized population from 2007 to 2008 National Health and Nutritional Examination Survey (NHANES). A total of 3204 study participants aged ≥35 years were stratified into four groups, using a self-reported history of asthma and data from spirometry: asthma-COPD overlap (ACO) ( n  = 70, 2.2%), asthma ( n  = 168, 5.2%), chronic obstructive pulmonary disease (COPD) ( n  = 412, 12.8%), and those without any OAD (normal) ( n  = 2554, 79.7%). After characterizing the baseline demographics and health status of the four groups, multivariate logistic regression analysis was performed to estimate the likelihood of sleep problems in adults after adjusting for age, gender, body mass index, smoking, alcohol, obstructive sleep apnea syndrome (OSAS), depression, and diabetes. The index sample was the normal group. Sleep problems were defined as any complaints which affect or involve sleep. Results The participants with COPD were older (62.0 ± 11.7 years) as compared to ACO (59.1 ± 11.3 years), asthma (53.6 ± 11.3), and normal groups (53.8 ± 12.1) ( p