Effects of d-cloprostenol administrations with 7.5 and 11.5-day intervals between administrations on pregnancy rates after artificial insemination in estrous cyclic dairy goats

• Published in: Animal reproduction science 2019-10, Vol.209, p.106172-106172, Article 106172
• Main Authors: Bonato, G.C., Maia, A.L.R.S., Côrtes, L.R., Oliveira, T.A., Arrais, A.M., Figueira, L.M., Oliveira, M.E.F., Souza-Fabjan, J.M.G., Fonseca, J.F.
• Format: Article
• Language: English
• Subjects: Animals; Cloprostenol - administration & dosage; Dairying; Drug Administration Schedule - veterinary; Estrous Cycle - drug effects; Estrous synchrony; Estrus Synchronization - methods; Female; Goats; Insemination, Artificial - methods; Insemination, Artificial - veterinary; Male; Ovulation; Ovulation - drug effects; PGF2α; Pregnancy; Pregnancy Rate; Pregnancy, Animal - drug effects; Time Factors; Ultrasonography
• ISSN: 0378-4320; 1873-2232
• DOI: 10.1016/j.anireprosci.2019.106172

This study was conducted to evaluate effects of two administrations of d-cloprostenol at different intervals to synchronize the time of estrus and ovulation among estrous cyclic goats. In Experiment 1, 32 does were treated with 30 μg d-cloprostenol at 7.5 (T7.5, n = 16) or 11.5-day (T11.5, n = 16) intervals. In Experiment 2, the same treatments were administered and there was AI of the does (T7.5, n = 40 and T11.5, n = 38). In Experiment 1, ultrasonic assessments of ovaries were conducted at the time of the second administration of d-cloprostenol, every 12 h until detection of ovulation, and 7 days after estrous onset to detect the corpora lutea, as well as for pregnancy diagnosis 40 days after AI. In Experiment 1, the estrous response (90.6%, 29/32) was similar (P > 0.05) in both groups. Diameter of the largest follicle at the time of administration of the second dose was larger (P = 0.01) in the T7.5 than T11.5 group (7.0 compared with 5.7 mm), while the values for ovarian variables were similar (P > 0.05). In Experiment 2, the greatest (P