Palladium–NHC-Catalyzed Allylic Alkylation of Pronucleophiles with Alkynes

The palladium–N-heterocyclic carbene (NHC)-catalyzed allylic alkylation of various pronucleophiles with alkynes has been accomplished under mild conditions. The protocol exhibits broad functional group compatibility and high atom economy. Moreover, the catalytic process avoids the use of external ox...

Full description

Saved in:
Bibliographic Details
Published in:Organic letters 2019-10, Vol.21 (19), p.7956-7960
Main Authors: Ren, Wei, Zuo, Qian-Ming, Niu, Yan-Ning, Yang, Shang-Dong
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The palladium–N-heterocyclic carbene (NHC)-catalyzed allylic alkylation of various pronucleophiles with alkynes has been accomplished under mild conditions. The protocol exhibits broad functional group compatibility and high atom economy. Moreover, the catalytic process avoids the use of external oxidants and acid as additives.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.9b02937