Advances in the Application of Magnetic Nanoparticles for Sensing

Magnetic nanoparticles (MNPs) are of high significance in sensing as they provide viable solutions to the enduring challenges related to lower detection limits and nonspecific effects. The rapid expansion in the applications of MNPs creates a need to overview the current state of the field of MNPs f...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2019-11, Vol.31 (48), p.e1904385-n/a
Main Authors: Gloag, Lucy, Mehdipour, Milad, Chen, Dongfei, Tilley, Richard D., Gooding, J. Justin
Format: Article
Language:English
Subjects:
biosensors
Detection
Fatigue limit
imaging
magnetic nanoparticles
Materials science
Nanoparticles
sensing
Sensors
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Summary:Magnetic nanoparticles (MNPs) are of high significance in sensing as they provide viable solutions to the enduring challenges related to lower detection limits and nonspecific effects. The rapid expansion in the applications of MNPs creates a need to overview the current state of the field of MNPs for sensing applications. In this review, the trends and concepts in the literature are critically appraised in terms of the opportunities and limitations of MNPs used for the most advanced sensing applications. The latest progress in MNP sensor technologies is overviewed with a focus on MNP structures and properties, as well as the strategies of incorporating these MNPs into devices. By looking at recent synthetic advancements, and the key challenges that face nanoparticle‐based sensors, this review aims to outline how to design, synthesize, and use MNPs to make the most effective and sensitive sensors. Advances in magnetic nanoparticle sensors have led to fast and selective detection of single molecules and rare cells. This review bridges the gap between the synthesis of magnetic nanoparticles and their use in sensing and imaging applications, which will be critical in the development of faster and more sensitive and specific sensors.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201904385