Phospholipid-based complex of raloxifene with enhanced biopharmaceutical potential: Synthesis, characterization and preclinical assessment

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Bibliographic Details
Published in:International journal of pharmaceutics 2019-11, Vol.571, p.118698-118698, Article 118698
Main Authors: Jain, Atul, Saini, Sumant, Kumar, Rajendra, Sharma, Teenu, Swami, Rajan, Katare, Om Prakash, Singh, Bhupinder
Format: Article
Language:English
Subjects:
Animals
Apoptosis - drug effects
Caco-2 Cells
Cell Survival - drug effects
Drug Delivery Systems
Drug Liberation
Erythrocytes - drug effects
Estrogen Antagonists - administration & dosage
Estrogen Antagonists - chemistry
Estrogen Antagonists - pharmacokinetics
Female
Hemolysis - drug effects
Humans
MCF-7 Cells
Molecular Docking Simulation
Phospholipids - administration & dosage
Phospholipids - chemistry
Phospholipids - pharmacokinetics
Raloxifene Hydrochloride - administration & dosage
Raloxifene Hydrochloride - chemistry
Raloxifene Hydrochloride - pharmacokinetics
Rats, Sprague-Dawley
Reactive Oxygen Species - metabolism
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ISSN:0378-5173
1873-3476
DOI:10.1016/j.ijpharm.2019.118698