Changes in the Regulatory T-Lymphocyte Counts in HIV-Infected Patients with a Discordant Response to Antiretroviral Therapy

We examined HIV-infected patients with different efficacies of immune system restoration during antiretroviral therapy. The study showed that against the background of low CD4+ T cell counts, subjects with a discordant immunologic response (patients with

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Bibliographic Details
Published in:Doklady. Biological sciences 2019-07, Vol.487 (1), p.128-131
Main Authors: Saidakova, E. V., Shmagel, K. V., Shmagel, N. G., Korolevskaya, L. B., Chereshnev, V. A.
Format: Article
Language:English
Subjects:
Adult
Anti-HIV Agents - pharmacology
Anti-HIV Agents - therapeutic use
Antiretroviral drugs
Antiretroviral therapy
Biomedical and Life Sciences
CD4 antigen
CD4 Lymphocyte Count
Cell Biology
Drug therapy
Evolutionary Biology
Female
HIV
HIV Infections - blood
HIV Infections - drug therapy
Human immunodeficiency virus
Humans
Immune system
Immunodeficiency
Life Sciences
Lymphocytes
Lymphocytes T
Male
Plant Sciences
T-Lymphocytes, Regulatory - drug effects
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Description
Summary:We examined HIV-infected patients with different efficacies of immune system restoration during antiretroviral therapy. The study showed that against the background of low CD4+ T cell counts, subjects with a discordant immunologic response (patients with
ISSN:0012-4966
1608-3105
DOI:10.1134/S0012496619040082