Risks of Dysglycemia Over the First 4 Years After a Hypertensive Disorder of Pregnancy

• Published in: Canadian journal of diabetes 2019-12, Vol.43 (8), p.587-593
• Main Authors: Wen, Chuan, Metcalfe, Amy, Anderson, Todd, Sigal, Ronald J., Johnson, Jo-Ann, Carson, Michael, Nerenberg, Kara A.
• Format: Article
• Language: English
• Subjects: Adult; Alberta - epidemiology; Case-Control Studies; diabète de type 2; dygslycemia; dysglycémie; dépistage; Female; Follow-Up Studies; grossesse; Humans; Hypertension, Pregnancy-Induced - epidemiology; hypertensive disorders of pregnancy; preeclampsia; pregnancy; Premature Birth; prééclampsie; screening; troubles hypertensifs de la grossesse; type 2 diabetes
• ISSN: 1499-2671; 2352-3840
• DOI: 10.1016/j.jcjd.2019.07.150

Women with the hypertensive disorders of pregnancy (HDP) (preeclampsia [PE] and gestational hypertension [GHTN]) have increased risks of future diabetes. Postpartum glycemic testing offers early identification and treatment of dysglycemia, but evidence-based recommendations for this high-risk population are lacking. The objective of this study was to describe the risks of developing dysglycemia in women with normotensive and hypertensive pregnancies over the first 4 years postpartum. The Discharge Abstract Database was used to identify women who delivered singleton live-born infants in Calgary, Alberta, Canada, between January 2010 and December 2012 (N=27,300). This was linked with Calgary Laboratory Services (for glycemic tests) and the Pharmaceutical Information Network databases (for antidiabetes medication prescriptions) over the first 4 years postpartum. Logistic regression analyses compared glycemic testing and results were adjusted for maternal age, gestational age, parity and the Pampalon deprivation index. Women with HDP had more glycemic testing (GHTN 67.8% and PE 69.9% vs normotensive 60.9%; p