Use of magnetic resonance index of activity (MaRIA) in the preoperative assessment of small bowel Crohn's disease

Accurate quantification of the inflammatory activity in Crohn's Disease is essential to determine adequate treatment for each patient. The aim of the present study is to assess the correlation between the pre-operative Magnetic Resonance Index of Activity (MaRIA) and the histologic degree of in...

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Bibliographic Details
Published in:Cirugia española (English ed.) 2019-12, Vol.97 (10), p.582-589
Main Authors: Pous-Serrano, Salvador, Frasson, Matteo, Pàmies-Guilabert, José, Rudenko, Polina, Puchades-Román, Icíar, Beltrán, Belén, Nos Mateu, Pilar, García-Granero, Eduardo
Format: Article
Language:eng ; spa
Subjects:
Adolescent
Adult
Crohn Disease - diagnostic imaging
Crohn Disease - pathology
Crohn Disease - surgery
Female
Fibrosis - diagnostic imaging
Fibrosis - pathology
Humans
Inflammation - diagnostic imaging
Inflammation - pathology
Intestinal Diseases - pathology
Magnetic Resonance Imaging - methods
Male
Middle Aged
Preoperative Care - instrumentation
Preoperative Care - methods
Prospective Studies
Sensitivity and Specificity
Severity of Illness Index
Young Adult
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Summary:Accurate quantification of the inflammatory activity in Crohn's Disease is essential to determine adequate treatment for each patient. The aim of the present study is to assess the correlation between the pre-operative Magnetic Resonance Index of Activity (MaRIA) and the histologic degree of inflammation from surgically resected intestinal Crohn's Disease lesions. This is a prospective study including a consecutive case series of patients with small bowel Crohn's Disease, who underwent surgical resection. Magnetic resonance enterography was performed in the 3months prior to surgery, applying a pre-established protocol. Relative contrast enhancements, wall thickness, presence of edema or ulcerations were the parameters used to calculate the MaRIA Index. All patients underwent surgery and every specimen was analyzed. The modified Chiorean classification was applied for the histological analysis and an ordinal regression analysis was used to correlate MaRIA and the grade of inflammation for each lesion. 59 lesions from 35 different patients were analyzed. The degree of inflammation of the lesions was statistically correlated to the MaRIA values (P=.002). The MaRIA index was significantly different (P
ISSN:2173-5077
DOI:10.1016/j.ciresp.2019.06.018