Oral appliance therapy in obstructive sleep apnea and snoring - systematic review and new directions of development

Objective: Oral appliance therapy is a non-invasive treatment that offers a wide variety of oral devices for the treatment of obstructive sleep apnea (OSA). The present review focuses on the effectiveness of mandibular advancement devices for the treatment of OSA. Methods: A systematic review based...

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Bibliographic Details
Published in:Cranio 2021-11, Vol.39 (6), p.472-483
Main Authors: Ilea, Aranka, Timuș, Daniela, Höpken, Julian, Andrei, Vlad, Băbțan, Anida-Maria, Petrescu, Nausica Bianca, Câmpian, Radu Septimiu, Boșca, Adina Bianca, Șovrea, Alina Simona, Negucioiu, Marius, Mesaros, Anca
Format: Article
Language:English
Subjects:
Dentistry
mandibular advancement device
mandibular advancement splint
mandibular repositioning device
Obstructive sleep apnea
oral appliance
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Summary:Objective: Oral appliance therapy is a non-invasive treatment that offers a wide variety of oral devices for the treatment of obstructive sleep apnea (OSA). The present review focuses on the effectiveness of mandibular advancement devices for the treatment of OSA. Methods: A systematic review based on the PRISMA checklist was carried out. A detailed electronic database search was conducted using "Obstructive sleep apnea" AND "Oral appliance" AND "Dentistry" as keywords. Results: The initial search in the electronic databases resulted in a total of 262 papers. After the title and abstract analysis and full-text review, the number of eligible papers was reduced to 15. Conclusion: The mandibular advancement device is an effective treatment, improving the Apnea Hypopnea Index and the symptoms of patients with OSA in 92% of the subjects from all the investigated studies. The future may include the integration of a biosensor for the diagnosis and follow-up. Abbreviations: OSA: Obstructive sleep apnea; MADs: Mandibular advancement devices; CPAP: Continuous positive airway pressure; OAT: Oral appliance therapy; MRD: Mandibular repositioning devices; MAS: Mandibular advancement splints; MAA: Mandibular advancement appliances; OA: Oral appliances; AASM: American Academy of Sleep Medicine; AHI: Apnea-hypopnea index; EEG: Sleep-related breathing disorder SRBD; Electroencephalogram; EOG: Electrooculogram; ECG: Electrocardiogram; QOL: Quality of life; TMJ: Temporomandibular joint.
ISSN:0886-9634
2151-0903
DOI:10.1080/08869634.2019.1673285