Rate of colorectal neoplasia in patients with Hodgkin lymphoma

Aim Survivors of Hodgkin lymphoma (HL) are at increased risk of breast, lung, thyroid, stomach, pancreatic and colon cancer. There is limited information on the utility of endoscopic screening for colon cancer. We aimed to describe the adenoma detection rate (ADR) in patients with HL to determine th...

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Bibliographic Details
Published in:Colorectal disease 2020-02, Vol.22 (2), p.154-160
Main Authors: Abu‐Sbeih, H., Ali, F. S., Tang, T., Coronel, E., Lee, H. J., Pande, M., Bresalier, R. S., Raju, G. S., Wang, Y.
Format: Article
Language:English
Subjects:
Adenocarcinoma
Adenoma
Adenoma - diagnosis
Adenoma - pathology
Adult
Breast
Colon - pathology
colon adenoma
Colon cancer
Colonic Polyps - diagnosis
Colonic Polyps - etiology
Colonoscopy
Colorectal cancer
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - secondary
Dysplasia
Early Detection of Cancer - statistics & numerical data
Female
Health risk assessment
Hodgkin Disease - complications
Hodgkin Disease - pathology
Hodgkin lymphoma
Hodgkin's lymphoma
Humans
Invasiveness
Lymphoma
Male
Middle Aged
Multivariate Analysis
Pancreas
Pancreatic cancer
Polyps
Rectum - pathology
Retrospective Studies
Risk Factors
screening
surveillance
Thyroid
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Summary:Aim Survivors of Hodgkin lymphoma (HL) are at increased risk of breast, lung, thyroid, stomach, pancreatic and colon cancer. There is limited information on the utility of endoscopic screening for colon cancer. We aimed to describe the adenoma detection rate (ADR) in patients with HL to determine the appropriate timing of colonoscopy screening. Method We retrospectively studied patients with HL who underwent colonoscopy between 2000 and 2017. Results A total of 251 patients underwent colonoscopy. Eighty (32%) patients had 151 colonic polyps. Thirty per cent of the polyps exhibited high‐grade dysplasia, and invasive colon adenocarcinoma was found in 10 patients. Patients with the nodular sclerosing subtype of HL had a significantly lower ADR than others (P = 0.002). The ADR was 5% in patients younger than 35 years (n = 64), 23% in patients between 35 and 40 years of age (n = 22), 39% in patients between 40 and 50 years of age (n = 51) and 46% in patients older than 50 years (n = 114).
ISSN:1462-8910
1463-1318
DOI:10.1111/codi.14855