The effect of nuchal cord on perinatal mortality and long-term offspring morbidity

Objective To evaluate perinatal and long-term cardiovascular and respiratory morbidities of children born with nuchal cord. Study design A large population-based cohort analysis of singleton deliveries was conducted. Maternal and birth characteristics, as well as cardiovascular and respiratory morbi...

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Bibliographic Details
Published in:Journal of perinatology 2020-03, Vol.40 (3), p.439-444
Main Authors: Masad, Roee, Gutvirtz, Gil, Wainstock, Tamar, Sheiner, Eyal
Format: Article
Language:English
Subjects:
692/499
692/700/1750/1747
Adult
Asphyxia neonatorum
Cardiovascular Diseases - etiology
Causes of
Cesarean section
Child development
Female
Follow-Up Studies
Health aspects
Humans
Infant, Newborn
Kaplan-Meier Estimate
Maternal Age
Meconium aspiration syndrome
Medicine
Medicine & Public Health
Morbidity
Mortality
Nuchal Cord - complications
Nuchal Cord - mortality
Offspring
Pediatric research
Pediatric Surgery
Pediatrics
Perinatal Mortality
Population studies
Pregnancy
Pregnancy Outcome
Proportional Hazards Models
Regression analysis
Regression models
Respiratory Tract Diseases - etiology
Retrospective Studies
Risk factors
Survival
Umbilical cord
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Summary:Objective To evaluate perinatal and long-term cardiovascular and respiratory morbidities of children born with nuchal cord. Study design A large population-based cohort analysis of singleton deliveries was conducted. Maternal and birth characteristics, as well as cardiovascular and respiratory morbidity incidence were evaluated. Kaplan–Meier survival curves were used to compare cumulative hospitalization incidence between groups. Cox regression models were used to control for possible confounders and follow-up length. Results 243,682 deliveries were included. Of them, 34,332 (14.1%) were diagnosed with nuchal cord. Perinatal mortality rate was comparable between groups (0.5 vs. 0.6%, p  = 0.16). Kaplan–Meier survival curves demonstrated no significant differences in cumulative cardiovascular or respiratory morbidity incidence between groups (log rank p  = 0.69 and p  = 0.10, respectively). Cox regression models reaffirmed a comparable risk for hospitalization between groups (aHR = 0.99 (95% CI 0.85–1.14, p  = 0.87) and aHR = 0.97 (95% CI 0.92–1.02, p  = 0.28). Conclusions Nuchal cord is not associated with higher rate of perinatal mortality nor long-term cardiorespiratory morbidity.
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-019-0511-x