Orthostatic and Exercise Effects in Children Years After Kawasaki Disease

• Published in: Pediatric cardiology 2020, Vol.41 (1), p.24-30
• Main Authors: Nakamura, Yoshihiro, Hama, Takehiro, Nakamura, Yoshie, Tsukada, Hideki, Oda, Yoichiro, Awa, Shoichi
• Format: Article
• Language: English
• Subjects: Aneurysms; Arterial Pressure - physiology; Cardiac Surgery; Cardiology; Case-Control Studies; Child; Children's furniture; Comparative analysis; Exercise - physiology; Exercise Test - methods; Exercise Tolerance - physiology; Female; Heart beat; Heart Rate - physiology; Hemodynamics - physiology; Humans; Kawasaki disease; Male; Medical research; Medicine; Medicine & Public Health; Medicine, Experimental; Mucocutaneous Lymph Node Syndrome - physiopathology; Original Article; Retrospective Studies; Vascular Surgery
• ISSN: 0172-0643; 1432-1971
• DOI: 10.1007/s00246-019-02216-x

The long-term orthostatic and/or exercise hemodynamic effects in children years after Kawasaki disease (KD) were studied using clinical data from the treadmill exercise test (TMET). Heart rate (HR) and blood pressures (BPs) recorded in TMET were compared between two age, gender, and body scale-matched groups of patients with and without a history of KD. The KD group included 60 patients (9.8 ± 2.7 years old) 6.6 ± 2.6 years after KD without coronary arterial aneurysm. The non-KD group included 60 children (10.2 ± 2.7 years old) with other diagnoses. The exercise tolerance in TMET was not statistically different between the two groups. The KD group had a faster HR on standing than the non-KD group by 8.6% (101.5 ± 12.2 vs. 93.5 ± 15.9 bpm, respectively; P