Molecularly imprinted polypyrrole based electrochemical sensor for selective determination of 4-ethylphenol

• Published in: Talanta (Oxford) 2020-01, Vol.207, p.120351-120351, Article 120351
• Main Authors: Domínguez-Renedo, Olga, Navarro-Cuñado, A. Marta, Arnáiz-Lozano, Victor, Alonso-Lomillo, M. Asunción
• Format: Article
• Language: English
• Subjects: 4-ethylphenol; Electrochemical sensor; Molecularly imprinted polymer; Polypyrrole; Wine
• ISSN: 0039-9140; 1873-3573
• DOI: 10.1016/j.talanta.2019.120351

This work describes the development of an electrochemical sensor based on a molecularly imprinted polymer (MIP) for sensitive and selective determination of 4-ethylphenol in wine. The sensor has been built by means of the electrosynthesis of the MIP on a glassy carbon electrode surface using cyclic voltammetry. The electropolymerization has been performed in the presence of 4-ethylphenol and pyrrole as template molecule and functional monomer, respectively. The influence of the molar ratios of template molecules to functional pyrrole monomers and the time needed to remove the template have been optimized taking into account the differential pulse voltammetric response of 4-ethylphenol. Under the optimal experimental conditions the developed MIP/GCE sensor shows good capability of detection (0.2 μM, α = β = 0.05) and reproducibility (3.0%) in the concentration range from 0.2 to 34.8 μM. The influence of possible interfering species in the analytical response has been studied and the sensor has successfully been applied to the determination of 4-ethylphenol in different wine samples. [Display omitted] •Voltammetric determination of 4-ethylphenol using a molecularly imprinted polypyrrole modified GCE.•High sensitivity and selectivity with a wide linear range and good capability of detection.•Successful determination of 4-ethylphenol in wine samples.