Intense Pulsed Light Therapy for Patients with Meibomian Gland Dysfunction and Ocular Demodex Infestation

Summary To observe the clinical changes of meibomian gland dysfunctipn (MGD) and ocular Demodex infestation after intense pulsed light (IPL) treatment to further examine the mechanism of IPL treating patients with MGD and ocular Demodex infestation. The medical records of 25 patients (49 eyes) with...

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Bibliographic Details
Published in:Current medical science 2019-10, Vol.39 (5), p.800-809
Main Authors: Cheng, Sheng-nan, Jiang, Fa-gang, Chen, Hua, Gao, Hui, Huang, Yu-kan
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Animals
Eyelids - parasitology
Eyelids - pathology
Eyelids - radiation effects
Female
Humans
Intense Pulsed Light Therapy - methods
Male
Medicine
Medicine & Public Health
Meibomian Gland Dysfunction - parasitology
Meibomian Gland Dysfunction - pathology
Meibomian Gland Dysfunction - therapy
Meibomian Glands - parasitology
Meibomian Glands - pathology
Meibomian Glands - radiation effects
Middle Aged
Mite Infestations - parasitology
Mite Infestations - pathology
Mite Infestations - therapy
Mites - pathogenicity
Mites - physiology
Mites - radiation effects
Retrospective Studies
Tears - parasitology
Tears - radiation effects
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Summary:Summary To observe the clinical changes of meibomian gland dysfunctipn (MGD) and ocular Demodex infestation after intense pulsed light (IPL) treatment to further examine the mechanism of IPL treating patients with MGD and ocular Demodex infestation. The medical records of 25 patients (49 eyes) with MGD treated with IPL, were retrospectively examined to determine outcomes. Associated ocular-surface parameters (ocular surface disease index, OSDI; lipid layer thickness, LLT; noninvasive first breakup time, NIF-BUT; noninvasive average breakup time, NIAvg-BUT; tear film breakup area, TBUA; Schirmer I Test, SIT; corneal fluorescein staining, CFS), eyelid margin abnormalities, meibum quality and expressibility, MG morphological parameters (macrostructure and microstructure), and the number of Demodex infestation were examined before and after treatment. The MG microstructure and the Demodex infestation were examined via in vivo confocal microscopy (IVCM). The results showed that there were statistically significant differences in associated ocular-surface parameters (all P
ISSN:2096-5230
2523-899X
DOI:10.1007/s11596-019-2108-1