LEAP2: A novel regulator of food intake and body weight?

A new study is the first to investigate the relationship between liver-enriched antimicrobial peptide-2 (LEAP2) and different metabolic states, and highlights the reciprocal relationship between LEAP2 and ghrelin (known as the ‘hunger hormone’ for its role in stimulating appetite). These findings co...

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Bibliographic Details
Published in:Nature reviews. Gastroenterology & hepatology 2019-12, Vol.16 (12), p.711-712
Main Authors: Schalla, Martha A., Stengel, Andreas
Format: Article
Language:English
Subjects:
692/163/2743/393
692/4020/198
692/699/317
692/700/2814
Animals
Antimicrobial peptides
Appetite
Biomedicine
Body Weight
Cholecystokinin
Eating
Food intake
Gastroenterology
Ghrelin
Hepatology
Humans
Hunger
Liver
Medical colleges
Medicine
Medicine & Public Health
Mice
News & Views
news-and-views
Obesity
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Description
Summary:A new study is the first to investigate the relationship between liver-enriched antimicrobial peptide-2 (LEAP2) and different metabolic states, and highlights the reciprocal relationship between LEAP2 and ghrelin (known as the ‘hunger hormone’ for its role in stimulating appetite). These findings could have important implications given the worldwide increase in obesity since 1975.
ISSN:1759-5045
1759-5053
DOI:10.1038/s41575-019-0224-9