Multiple atypical thymic carcinoids with paraneoplastic giant cell arteritis

Multiple thymic carcinoids are rare, and giant cell arteritis (GCA) is one of the less recognized paraneoplastic diseases. The co-occurrence of these two diseases is therefore extremely rare. We report herein a patient with multiple atypical thymic carcinoids and asymptomatic paraneoplastic GCA. All...

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Bibliographic Details
Published in:General thoracic and cardiovascular surgery 2020-10, Vol.68 (10), p.1212-1215
Main Authors: Nakayama, Takashi, Katagiri, Sayaka, Kikkawa, Takuma, Obara, Tetsuya, Mori, Tatsuo, Kiriu, Takahiro
Format: Article
Language:English
Subjects:
Aged
Asymptomatic
Biopsy
Carcinoid Tumor - complications
Carcinoid Tumor - pathology
Carcinoid Tumor - secondary
Carcinoid Tumor - surgery
Cardiac Surgery
Cardiology
Case Report
Case reports
Conflicts of interest
Female
Giant Cell Arteritis - diagnostic imaging
Giant Cell Arteritis - etiology
Humans
Medical prognosis
Medicine
Medicine & Public Health
Metastasis
Neoplasms, Multiple Primary - complications
Neoplasms, Multiple Primary - pathology
Neoplasms, Multiple Primary - surgery
Paraneoplastic Syndromes - diagnostic imaging
Paraneoplastic Syndromes - etiology
Positron-Emission Tomography
Steroids
Surgical Oncology
Thoracic Surgery
Thymus gland
Thymus Neoplasms - complications
Thymus Neoplasms - pathology
Thymus Neoplasms - secondary
Thymus Neoplasms - surgery
Tomography
Tumors
Vein & artery diseases
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Summary:Multiple thymic carcinoids are rare, and giant cell arteritis (GCA) is one of the less recognized paraneoplastic diseases. The co-occurrence of these two diseases is therefore extremely rare. We report herein a patient with multiple atypical thymic carcinoids and asymptomatic paraneoplastic GCA. All the thymic carcinoids were diagnosed histopathologically as atypical thymic carcinoids with an intrathymic metastasis. Treatment consisted of a complete tumor resection followed by observation of the GCA without any adjuvant therapy. Subsequent positron emission tomography revealed a decrease in F-fludeoxyglucose accumulation in the systemic arteries. Based on these findings, paraneoplastic GCA was diagnosed. Thymic carcinoids rarely involve intrathymic metastasis or cause neopleonastic GCA. However, when they do, a complete tumor resection is the best option for management.
ISSN:1863-6705
1863-6713
DOI:10.1007/s11748-019-01230-3